Nigeria Developing Her Coronavirus Vaccine Would Be Amazing – NAFDAC

The National Agency for Food and Drug Administration and Control (NAFDAC) is set to partner with indigenous scientists in the development of drugs or vaccines against the coronavirus disease (COVID-19) in Nigeria.

Prof. Mojisola Adeyeye, NAFDAC Director-General revealed this in a recent statement.

According to her, NAFDAC’s interventions would aid documentation of such initiatives for global recording as potential vaccines or drugs that is in process or safety testing.

She added that even if it would be an amazing achievement if Nigeria can develop her own coronavirus vaccine, certain guidelines have to be followed.

Her words, “It will be a great thing if Nigeria develops her vaccine, but all the steps stated above will have to be followed,”

“That testing will involve use of the virus and then animals. If all goes well, the researchers will then plan for clinical trial which will take a long time from 18 months to years.”

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Coronaviruses are a group of related viruses that cause diseases in mammals and birds. In humans, coronaviruses cause respiratory tract infections that can be mild, such as some cases of the common cold (among other possible causes, predominantly rhinoviruses), and others that can be lethal, such as SARS, MERS, and COVID-19. Symptoms in other species vary: in chickens, they cause an upper respiratory tract disease, while in cows and pigs they cause diarrhea. There are yet to be vaccines or antiviral drugs to prevent or treat human coronavirus infections.

Coronaviruses constitute the subfamily Orthocoronavirinae, in the family Coronaviridae, order Nidovirales, and realm Riboviria. They are enveloped viruses with a positive-sense single-stranded RNA genome and a nucleocapsid of helical symmetry. The genome size of coronaviruses ranges from approximately 27 to 34 kilobases, the largest among known RNA viruses. The name coronavirus is derived from the Latin corona, meaning “crown” or “halo”, which refers to the characteristic appearance reminiscent of a crown or a solar corona around the virions (virus particles) when viewed under two-dimensional transmission electron microscopy, due to the surface covering in club-shaped protein spikes.

Human coronaviruses were first discovered in the late 1960s. The earliest ones discovered were an infectious bronchitis virus in chickens and two in human patients with the common cold (later named human coronavirus 229E and human coronavirus OC43). Other members of this family have since been identified, including SARS-CoV in 2003, HCoV NL63 in 2004, HKU1 in 2005, MERS-CoV in 2012, and SARS-CoV-2 (formerly known as 2019-nCoV) in 2019. Most of these have involved serious respiratory tract infections.

The name “coronavirus” is derived from Latin corona, meaning “crown” or “wreath”, itself a borrowing from Greek κορώνη korṓnē, “garland, wreath”. The name refers to the characteristic appearance of virions (the infective form of the virus) by electron microscopy, which have a fringe of large, bulbous surface projections creating an image reminiscent of a crown or of a solar corona. This morphology is created by the viral spike peplomers, which are proteins on the surface of the virus.